Tau pathology refers to the accumulation of abnormal tau protein in the brain, which is commonly associated with neurodegenerative diseases such as Alzheimer's disease, frontotemporal lobar degeneration, and progressive supranuclear palsy. Tau protein plays a crucial role in maintaining the structure and function of nerve cells, and abnormal tau accumulation can lead to the formation of neurofibrillary tangles and neuronal dysfunction. Research in the area of tau pathology aims to understand the underlying mechanisms of tau protein aggregation, its role in disease progression, and potential therapeutic interventions to target tau pathology and slow down or halt the degenerative process. This research involves studying the molecular and cellular pathways involved in tau aggregation, developing animal models to study tau pathology, and investigating potential biomarkers for early diagnosis and monitoring of tau-related diseases. Additionally, researchers are exploring novel therapeutic approaches, such as immunotherapy and small molecule inhibitors, to target and reduce tau pathology in neurodegenerative diseases.